Serotonin
CAS number:50-67-9
-
Molecular Formula:
C10H12N2O
-
Molecular Weight:
176.21g/mol
-
Brief Introduction:
Serotonin, also known as 5-hydroxytryptamine (5-HT), is a crucial neurotransmitter involved in both central and peripheral nervous system functions. It plays a significant role in regulating mood, cognition, and sensory processing, and is implicated in various physiological processes such as metabolism and tissue regeneration. Recent studies highlight its importance in model-based learning, where it helps refine cognitive maps by integrating multidimensional reward expectations, such as timing, probability, and magnitude. Serotonin neurons in the dorsal raphe nucleus (DRN) exhibit sustained activity during reward anticipation, which contrasts with the phasic firing of dopamine neurons, suggesting complementary roles in learning and behavior. Dysregulation of serotonin is associated with psychiatric disorders, including depression and anxiety, underscoring its therapeutic potential. Additionally, serotonin's interaction with gut microbiota-derived metabolites further links it to broader systemic functions.
Biogenic Amines
Serotonin is a biogenic monoamine, a group of naturally occurring amines derived from amino acids.
Monoamines
Serotonin contains a single amine group, hence classified as a monoamine neurotransmitter, alongside dopamine and norepinephrine.
Indoleamines
Serotonin contains an indole ring (a fused ring consisting of a benzene and a pyrrole), placing it in this subclass.
Endogenous Compounds
Serotonin is endogenously produced in the human body (mainly in the gastrointestinal tract and brain).
50-67-9 Suppliers
Guangzhou Chemical Reagent Factory
With more than 1200 product varieties and over 3000 specifications, Guangzhou Chemical Reagent Factory serves a wide range of sectors including scientific research institutions, inspection and quarantine services, environmental monitoring, biopharmaceuticals, electronics, electroplating, healthcare, aerospace technology, new energy, and more.
